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Hypercalcemia from calcitriol (1,25-dihydroxyvitamin D) overproduction—seen with certain lymphomas—responds particularly well to glucocorticoids, which inhibit extrarenal calcitriol synthesis and intestinal calcium absorption. Initial management includes aggressive isotonic IV fluids to correct dehydration and enhance calciuresis. Calcitonin provides a rapid but transient reduction and can bridge to definitive control. Bisphosphonates or denosumab may be added to suppress bone resorption, though in calcitriol-mediated cases steroids are pivotal. Calcitonin alone (Option C) relieves symptoms briefly but is insufficient. Dialysis (Option D) is reserved for refractory, life-threatening hypercalcemia with renal failure or fluid overload. The APRN should monitor electrolytes (risk of hypophosphatemia), mental status, urine output, and consider lymphoma-directed therapy for durable control. Educate on hydration and review medications that raise calcium (thiazides, vitamin D), adjusting as needed.