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Health literacy and numeracy vary widely and directly affect informed consent. Presenting data using absolute risks (e.g., 5-year recurrence risk decreases from 20% to 15%) and natural frequencies (“5 fewer people out of 100”) improves comprehension compared with relative risk alone, which can exaggerate perceived benefit. Layering information with simple visuals (icon arrays, bar charts) and plain language avoids jargon and supports shared decision-making. The teach-back method—asking patients to explain in their own words—verifies understanding and identifies gaps to address. Providing dense literature without guidance (Option C) burdens the patient and may increase confusion. Avoiding risks (Option D) violates informed consent. Relative risk alone (Option A) is misleading. The APRN should explore values and preferences, check for cultural/linguistic needs (use interpreters, translated materials), pace information across visits when possible, and invite a support person. Document the conversation, decisions made, and resources provided, and ensure a contact pathway for follow-up questions.