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Environmental cleaning is essential to prevent blood-borne pathogen transmission (e.g., HBV, HCV) and cross-contamination. The correct process begins with donning appropriate PPE (gloves, gown/apron, face protection as needed). First remove visible soil using a detergent or cleaning step; disinfection is less effective if organic material remains. Then apply an EPA-registered disinfectant approved by the facility (often a diluted bleach or other tuberculocidal product), ensuring the surface remains wet for the full manufacturer-specified contact time. High-touch areas include chair armrests, machine touchscreens/knobs, clamps, and surrounding surfaces. Dispose of single-use supplies, replace barriers, and segregate clean versus contaminated items to avoid re-contamination. Perform hand hygiene after removing PPE. Water alone (B) does not disinfect. Alcohol alone (C) may not be effective on blood-contaminated surfaces and lacks necessary contact time. Changing lines (D) does not eliminate contamination on external surfaces. Thorough documentation and adherence to policy support infection prevention and survey readiness.