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Comprehensive and Detailed Explanation:

Pressure injuries result from sustained mechanical loading that exceeds tissue tolerance. Once an ischial ulcer has healed, recurrence prevention centers on eliminating or redistributing the causative pressure. This includes a properly fitted wheelchair cushion, correct pelvic posture, regular pressure-relief maneuvers, and patient or caregiver education. Topical antibiotics have no preventive role on intact skin and promote resistance. Permanent bed rest creates new pressure risks and functional decline. Systemic corticosteroids impair healing and are not indicated for prevention. Etiological Considerations domain requires the specialist to address the root mechanical cause rather than focusing solely on the wound. Comprehensive discharge planning and interdisciplinary collaboration (physical therapy, occupational therapy, seating specialists) are essential to sustain healing and reduce the high recurrence rates associated with pressure injuries.