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Comprehensive and Detailed Explanation:

When a project activity is delayed, the planner should first assess how that delay affects other dependent tasks. CMP-aligned project management requires understanding task relationships, schedule dependencies, critical milestones, and potential consequences before taking corrective action.

In this scenario, keynote confirmation may affect several downstream activities, including agenda publication, promotional campaigns, website updates, and attendee communications. Evaluating these dependencies allows the planner to determine whether schedule adjustments, contingency actions, or stakeholder notifications are necessary.

Ignoring the issue increases the likelihood of larger delays. Cancelling all marketing activities would be excessive without first understanding the impact. Immediately replacing the speaker may also create unnecessary disruption if the confirmation can still be obtained within an acceptable timeframe.

Effective project management requires informed decision-making based on schedule impact and project priorities.

Therefore, assessing the impact on dependent project activities is the best first step because it provides the information needed to determine an appropriate response.