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Specimens must be transported in containers that prevent leakage and exposure and are clearly marked as biohazard. The standard is a leak-resistant biohazard transport bag with a separate outer pocket for paperwork so requisitions are not contaminated if a tube leaks. Tubes should remain capped and positioned upright in a rack or protective sleeve to minimize agitation, foam, and contact with stoppers, which reduces hemolysis and additive carryover. Option A risks spills and exposures; Option B disguises hazards and impedes proper handling during spills or inspections; Option D is unsafe and noncompliant. Additional controls include using rigid carriers or validated pneumatic tube canisters with absorbent material when appropriate, honoring exclusion lists (e.g., some blood bank, CSF, warm-kept or iced specimens), and prompt delivery. Proper packaging protects staff, preserves specimen integrity, and satisfies regulatory standards—core competencies for phlebotomy practice.