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The doffing sequence is designed to remove the most contaminated items first while avoiding contact with mucous membranes. Gloves are typically the most contaminated and should be removed first, followed by eye protection (goggles/face shield) without touching the front surfaces. Next, the gown is removed by breaking ties and rolling it inside-out away from the body. The mask or respirator is removed last by handling ties or ear loops only, avoiding contact with the front. Hand hygiene is performed immediately after removing all PPE and again after leaving the patient care area if required. Option B reflects this logic and is consistent with widely taught infection-prevention practices. Altering the order (Options A, C, or D) can increase risk by touching the face before removing contaminated gloves or by handling facial PPE before de-gowning. Consistent, correct PPE removal reduces healthcare-associated transmission risks and is a tested competency for phlebotomists, who frequently enter isolation rooms.