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Post-treatment surveillance aims to detect resectable recurrence and metachronous neoplasia. Standard follow-up includes interval history/physical and CEA testing every 3–6 months for the first 2 years (highest recurrence risk), then every 6 months to year 5. Cross-sectional imaging (CT chest/abdomen/pelvis) is typically performed annually for at least 3 years (some programs use every 6–12 months for higher risk), tailored to comorbidity and relapse risk. PET/CT (Option A) is not routine due to cost and false positives; reserve for equivocal findings. Colonoscopy should be performed at 1 year post-resection (or 3–6 months if the pre-op colon was not fully visualized), then at 3 years, and every 5 years thereafter if normal—shorter intervals for advanced adenomas. Limiting CEA to symptoms (Option C) or omitting surveillance (Option D) misses opportunities for early, potentially curable recurrence. APRNs coordinate scheduling, reinforce symptom awareness (weight loss, pain, bowel habit change), ensure lifestyle counseling, and document a survivorship care plan shared with primary care.