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Pregnancy reduces functional residual capacity and raises oxygen consumption; maternal hypoxemia rapidly compromises fetal oxygenation. Target SpO₂ ≥95% and maintain normocapnia for pregnancy (EtCO₂ ~30–35 mmHg), avoiding severe hypocapnia that can reduce uteroplacental flow. Left uterine displacement (manual or wedge) mitigates aortocaval compression, preserving venous return and cardiac output. Supine (A) worsens preload; EtCO₂ 25–30 mmHg is too low and risks uteroplacental vasoconstriction. Right tilt (C) increases caval compression, and permissive hypercapnia to EtCO₂ 45–50 mmHg risks fetal acidosis. Trendelenburg (D) impairs diaphragmatic mechanics and increases aspiration risk without improving perfusion. Maintain MAP sufficient for CPP/uteroplacental flow (often ≥65–70 mmHg), avoid hypotension and hypothermia, and communicate obstetric status to the receiving facility. Secure the airway meticulously—edema increases difficulty—and reassess ETT depth after every move due to cephalad diaphragm displacement.