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Evidence-based practice in psychology integrates three pillars: (1) best available research evidence (e.g., RCTs, systematic reviews, practice guidelines) matched to the client population and setting; (2) clinical expertise (assessment, case formulation, treatment planning, alliance management, cultural responsiveness); and (3) patient characteristics, values, and preferences (including cultural context, practical constraints, and treatment goals). Option B embodies this integration: select an empirically supported protocol for adolescent depression (e.g., CBT or IPT), adapt implementation respectfully to culture and preferences via shared decision-making, and use measurement-based care (e.g., PHQ-A, session ratings) to monitor progress and inform adjustments. Option A overrelies on manuals and neglects individualization and feedback. Option C prioritizes clinician preference over research and client factors. Option D lacks an empirical foundation and quality safeguards. EBP is an iterative, hypothesis-testing process: define the problem, choose a fit-for-purpose intervention, track outcomes, and adjust based on data. Organizational supports (training, supervision, fidelity checks) and attention to access and equity further strengthen implementation.

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